| Datum | Thuis | Score | Uit |
|---|---|---|---|
| Sat 12 Sep |  FC Twente |
2 - 0 |  Fortuna Sittard |
| Sun 20 Sep |  Feyenoord |
1 - 1 | FC Twente |
| Fri 25 Sep | FC Twente |
3 - 1 |  FC Groningen |
| Sat 3 Oct | FC Twente |
1 - 1 |  FC Emmen |
| Sat 17 Oct |  Willem II |
0 - 3 | FC Twente |
| Sat 24 Oct |  FC Utrecht |
2 - 1 | FC Twente |
| Sat 31 Oct | FC Twente |
5 - 1 |  PEC Zwolle |
| Sat 7 Nov |  ADO Den Haag |
2 - 4 | FC Twente |
| Sun 22 Nov | FC Twente |
1 - 1 |  PSV |
| Fri 27 Nov | FC Twente |
0 - 2 |  RKC Waalwijk |
| Sat 5 Dec |  Ajax |
1 - 2 | FC Twente |
| Sun 13 Dec | FC Twente |
1 - 3 |  AZ Alkmaar |
| Sat 19 Dec |  VVV-Venlo |
1 - 2 | FC Twente |
| Tue 22 Dec | FC Twente |
0 - 2 |  Sparta Rotterdam |
| Sat 9 Jan | FC Emmen |
1 - 4 | FC Twente |
| Thu 14 Jan | FC Twente |
1 - 3 | Ajax |
| Sun 17 Jan | FC Groningen |
2 - 2 | FC Twente |
| Sun 24 Jan | FC Twente |
0 - 1 | VVV-Venlo |
| Thu 28 Jan | Sparta Rotterdam |
0 - 0 | FC Twente |
| Sun 31 Jan | FC Twente |
0 - 0 |  SC Heerenveen |
| Sat 6 Feb | PSV |
3 - 0 | FC Twente |
| Sun 14 Feb |  Vitesse |
0 - 2 | FC Twente |
| Sun 21 Feb | FC Twente |
2 - 2 | Feyenoord |
| Sat 27 Feb |  Heracles |
2 - 2 | FC Twente |
| Sat 6 Mar | FC Twente |
1 - 1 | Willem II |
| Sat 13 Mar | AZ Alkmaar |
4 - 1 | FC Twente |
| Fri 19 Mar | SC Heerenveen |
0 - 0 | FC Twente |
| Sat 3 Apr | FC Twente |
1 - 2 | Vitesse |
| Sat 10 Apr | PEC Zwolle |
1 - 0 | FC Twente |
